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Women's Health | 04/07/2009 11:00 am

Say Good-Bye to Pap Smears, DNA Tests Are Better

By The Staff at wowOwow.com
© Shutterstock
Pap tests may be a thing of the past, according to a breakthrough study just published in the New England Journal of Medicine. Instead, DNA tests, which can detect the virus that causes cervical cancer, may be the test of choice for women 30 and over.

You’d still take a sample with a swab, as you do with a Pap smear, but the DNA test would be recommended just every three years (or perhaps even less often), rather than every year. And unlike the Pap smear, which looks for abnormal cancerous cells growing, the DNA swab finds the actual virus that causes the cancer in the first place. That’s why it could be better: Detection and treatment can be earlier.

The eight-year study of 130,000 women in India, sponsored by the Bill and Melinda Gates Foundation, also could be a major boon for women in undeveloped countries who have limited access to Pap tests and health care at the moment. The DNA test is cheap ($5) and can be processed by a machine, rather than being read by a pathologist (like a Pap). The fact that it doesn’t have to be done as often is another plus.

The study is "another nail in the coffin" for Pap smears, which will soon be of mainly historical interest," Stanford medical school professor Dr. Paul D. Blumenthal, told The New York Times. We’re counting the days.

11 Reader Comments (so far…) Sign In or Register to comment

rocky rocky
Thank goodness — and it seems thanks to the Gates Foundation as well and to the women of India who agreed to become part of the study. What an amazing thing for all of them to do! I’m so over false positives and the time and expense and anxiety they cause. This is great news, wOw. Thanks!
By rocky rocky on 04/07/2009 11:06 am
f p
Yes read this is the Times—excellent news.
By f p on 04/07/2009 11:19 am
EKA -

Gee, I so enjoyed having a stranger put a gloved hand up my Hoo Ha ….

 

God bless you, Bill Gates 

By EKA - on 04/07/2009 11:50 am
f p
lol sorry EKA but I just couldn’t resist :-)
By f p on 04/07/2009 11:56 am
nope wrong
The study was conducted with conventional cytology, not liquid based preparation.  A study currently underway in England will be released later this year proving liquid-based cytology better then the HPV test.  HPV 16 & 18 are the known causes to cervical cancers, they are not validated for detecting endometrial cancers, something paps aren’t validated for either but annual testing frequently picks up these cancers, moreover we are seeing an INCREASE in endometrial and endocervical adenocarcinomas.  This MD is probably getting a nice payoff from the company marketing the HPV test in order to establish some credibility to the test being better then a pap smear.  But i see no reporting on the number of squamous cell carcinomas as well as adenocarcinomas of the cervix that are HPV negative (yes they do exist).  How convenient for the author of this article, as well as the people quoted in it. 
By nope wrong on 04/07/2009 12:58 pm
C Hardy
This is great news for us women…
By C Hardy on 04/07/2009 12:59 pm
nope wrong
If anyone bothers to read the article in the New England Journal too, youll see that the people reading the pap smears were trained for 3-6 weeks….I didnt know 3 weeks of training is all you need to be a great doctor, sign me up!
By nope wrong on 04/07/2009 1:06 pm
Barbara B
Great to see this research and of course if this is the real deal great for all us women
By Barbara B on 04/07/2009 1:12 pm
Slinky Binx
Anything that is going to detect problems earlier is always a fantastic advancement!  Now, WHEN will they do something about mammograms? There has GOT to be a better, simpler, PAINLESS way to do this…
By Slinky Binx on 04/07/2009 2:48 pm
Juanita Ward

Slinky, you are so right, I might be black, but have no business turning black and blue after a mammogram. There have got to be a better way, It takes me 2-3 weeks to have full use of my arms again. To the Gates, all I can say is, thank you, Thank You! THANK YOU!!

 

By Juanita Ward on 04/07/2009 6:43 pm
Gramma J
I just quit going.  But if it’s only going to be an every three-year event, maybe I will get it done again.
By Gramma J on 04/07/2009 6:59 pm